The Human Spaceflight Mission Directorate leads NASA’s human spaceflight and space-enabling activities across low Earth orbit, the Moon, and beyond. The directorate provides unified leadership for the agency’s systems, operations, and architectures to deliver on the next era of human spaceflight.

In May 2026, NASA Administrator Jared Isaacman announced an agencywide realignment to increase mission focus and move out on the National Space Policy. These changes positioned the agency to better deliver on the nation’s highest‑priority objectives with speed and efficiency.

The realignment unified the Exploration Systems Development Mission Directorate and Space Operations Mission Directorate as the Human Spaceflight Mission Directorate.

Executive Director, Enterprise Operations: Brian Dewhurst

Executive Director, Enterprise Strategy: Alesyn Lowry

Director, Mission Alignment & Integration Office: Diana Oglesby

Director, Space Traffic Operational Risk Management Office: Alvin Drew

Manager, Commercial Access to Space: Bradley Smith

Overview

Leadership

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Human Spaceflight Mission Directorate

Humans In Space

Human Research in Space

Commercial Space

Launch Services Program